Ha!
In my experience breeding jackelopes in secret underground wildlife facilities, the really wild ones call for a little more gun than .458 has to offer. Something on the order of a .50 BMG would be right at home. Don't get me wrong, the .458 will probably kill one, I just wouldn't trust during a charge scenario. The 7 mm will only make em mad, and the sabertooth subspecies can hamstring you in a flash if you ain't careful with your shot placement.
Can't tell you how many of my colleagues I lost due to carelessness on their part. The jackelopes lull you into a senseof relaxation with their little brown eys, but you have to know they are always scheming a a way to kill you with claw, antler or fang.
Be careful out there. Their association with bigfoot is well documented, as they use jackelopes as sentries. So don't get caught killing one of those or you'll have a real mess on your hand.
Be careful out there.

So a .50 BMG eh? Will that be enough for rabbits too. I just want to reduce the chance of an attack after the shot. I'm so confused!!! Please help!!

I disagree on the .50 BMG. Jackalopes are elusive, fast, and highly aggressive -- a .50 BMG is just too big and unwieldy to swing around fast enough to engage the target. I prefer a Marlin 1895 guide gun in .45-70 loaded hot with 430 grain hard cast bullets from Garrett or Buffalo Bore. It's light and fast, and ghost ring sights get you on target in an instant. Those loads have also been known to penetrate lengthwise through brown bears and cape buffalo, and therefore provide just enough penetration for a Jackalope. The trick is to bait them in close with an open cooler filled with your favorite malt beverage.

I seen many Jackalope taken by a Pigmy with nothing more than his blowgun. It is all about shot placement.

Okay, here it is. I think I have the hardware I need. I ditched the .458 win mag. Got a marlin 1895 in .45-70. Replaced the walnut stock with a $1000 synthetic glass bedded camo stock, because all the gun rags that I read are telling me that an overpriced bedded synthetic stock is an absolute nesessity. Added a $5000 Schmidt & Bender tactical sniper scope 10X fixed. Backed up the scope with ghost ring sight. Added a picatinny rail to mount a $200 surefire weapons light as well as a tactical blowgun. I think I'm set. Will this set up allow me to take shots out to 1000 yards? I don't want to get too close. Now the question: will a 430 grain bullet from that .45-70 shoot flat enough to max point blank range at 1000 yards?? I'm still confused. Do I have all I need??

Which caliber goes BOOM as opposed to BANG. I want the one that goes BOOM.

I still think you're undergunned. The Boom to Bang ratio related to bore size and powder charge. More Bang means more faster, more boom means more slower. I'd want more bang than boom for dangerous game like jackelopes.

Can I kill a bear with the BANG or do I need a gun that goes BOOM for those?

Also I was attempting to clean my Marlin and spilled some Hoppes #9 on the stock. Will it disolve my synthetic stock? I just don't know much about this type of stuff!! Please help!

Dear Westernhunter.
Please don't do it! Hunting the elusive jackolope is not for the faint- nor roboust of heart. These are life taking creatures that many have gone in search of and FEW have returned. Truely it is not the size of the gun, but how you wield it!!

Now for gun cleaning. Those powder solvents are for wimps! Take the barrel of your gun and soak it in a 20% Bleach/Clorox solution for about a week. Once you remove it and let it dry, take a ball peen hammer (about 20 oz's) and beat the rust off the bbl. Now you truely have a "hammered bbl

You know, jackalopes are the most gentle of our Earth Mother's creatures, and deserve our protection. Thankfully, the Obama administration has declared them an endangered species and imposed stiff penalties on anyone who harrasses one. These penalties can include going for a drive with Ted Kennedy, opening a package from Bill Ayers, giving a speech without a teleprompter, or attending this year's Code Pink convention.

Expat wrote,

Expat, you forgot having a cigar with Bill Clinton!
As to the Jackelope the 458 would work but their nasty in a charge if you just wound them. I suggest you take a handgun in .22 short. When the wounded jackalope charges, shoot your hunting partner in the foot and run. You don't have to outrun the jackalope, you just have to outrun him.