If you can shoot a 454 casull you can handle the 460. it's pretty stout you got to hang on but it is managable. I have just the plain jane 460 XVR X-frame in stainless with the 8 3/4" barrle and a Leupold 3-7X scope.
Try to put your tree stand in a tree with plenty of background cover, keep the prevailing winds for that time of the year to your face, and take care of those pesky squeaks and creaks your stand may have developed while sitting in the shed. A good treestand lube can be made by heating petroleum jelly until it reaches a liquid form. Some hunters have reported success by including a cover scent in this mixture before applying it to their stands.