I read a lot discussion about which rifle/round is best for a particular quarry.
What I have found is it's best to set up a rifle for a particular method or size of game and use that rifle for what it is set up for.
I have a favor to the 30 caliber rounds. Bullet selection being the primary reason.
So, what I have come to do is pick three rounds in 30 caliber in three rifles that will meet my needs. Each set up to shoot one particular bullet. Each mounted with a scope that will work under the conditions that I will most likely have.
What I have come up with seems to work very well for my needs. They always shoot the same and it's makes my part in the field easier.
The first two are short cased rounds that have some limits in bullet size but the chosen bullet weights perform very well, for their requirement.
I took a bolt action 308win. Shortened the barrel to 20". Mounted a 4x scope on it. Found a good quality 150gr cup and core bullet that shoots well through it and use it for deer sized game under any hunting condition. It works well in the thick forests. On the open plains and up in the tundra. It's light to carry (easy). Has a MPBR, aim and shoot, of 0-300 yds.
I have a 300wsm that I mounted a 2x-7x scope on. Found a 180gr bonded core bullet that shoots well and use it for heavy hide and/or thick boned quarry. It works well under the conditions that I will have. Has a MPBR, aim and shoot, of 0-300 yds.
These first two rifle/rounds have almost identical trajectories but very different energy and bullet performance requirements.
The third choice I have come up with is a standard 30-06. Because, It has a longer case, I can load the heavy for caliber bullets and use it exclusively as a heavy brush rifle. Where the shots don't typically exceed 50 yds. The old eyes aren't what they used to be so I mounted a 1x-4x scope on it and load a 220gr partition type bullet. As a stopper it does wonders.
Any one of these rifle/rounds could be set up in different configurations for just about any combination of loads and uses. Any one of these rifle/round combinations could be used on any game in the lower 48 and some but, as said earlier. These combinations give me the consistency that is neccessary to do my part, with confidence in the firearm and load.