We're talking Africa, India, Austrailia and the Americas.
List your top one or two or three choices for what you'd consider the best choice for having only one rifle to hunt the whole world.
mine would be.
1) ruger M77 African in .375 ruger
2) Weatherby mark V in 30-378 wby mag
3) Winchester M70 in 338 win
barring several restrictions on caliber size for use on elephant, i think the last two would still be excellent choices for anything but the largest animal in the world. i would even place the performance of the 30-378 above the .338 win. This is why my top choice s at the top! i'd bet that .375 won't expand enough to destroy a deer as badly as you'd think it could. but who knows. let me know if you've tried it.