For my next project, I'm considering either a 9.3x64 Brenneke or a .358 norma mag. I've just got to figure out which will be cheaper in terms of both the rifle's construction and the acquisition or loading of ammo. The 9.3 brennee is basically equivalent to a 375 H&H mag, but shoots a .366 bullet giving it better sectional density. The .358 norma mag can be loaded to H&H energy levels, but it's not generally regarded as effective as the 9.3 or 375 H&H on big game...specifically, lion, and cape buffalo. I guess I'll also need to decide which fills a bigger void in my current arsenal (which could certainly change by the time I start the project).
For my area and hunting style, a .308 winchester is plenty, not to mention accurate and lightweight. So if I could only use one of my rifles, that one would be it. That said, I carry my .300 Wby if I believe there's a chance that I'll have to shoot 200+ yards at something like elk.
Finally decided on my final answer; My 9.3X74r SXS chapuis with the leupold vxIII 1.5X5 20 mm scope on top of a removable claw mount. Big enough for anything, and not too fast or big for deer or any other types of small game. It also shoots just flat enough for plains game (similar to the 375 H&H).
If you're lucky enough to be on private land and can leave your stand up during the off season you can tie an old piece of cloth or something of the sort to your stand. I like to use an old camo bandana that I have. That way the deer get used to the movement and eventually don't bother even looking up when there is slight movement. This may just give you the time to draw your bow or raise your gun without being detected.