Back in the '80s and early '90s both my Dad and I were lucky enough to tag bucks large enough for us to qualify for the Maine Big Bucks Club which requires a buck to field dress at at least 200 pounds on a certified scale. My Dad's tipped the scales at 217 and mine was 225.
Also, I didn't notice any mention in any of those links of Maine's all-time heaviest buck which was taken in 1955 by a fella named Horace Hinkley and weighed 355 pounds on a certified scale (if memory serves me). Most sources say this is the 2nd largest whitetail buck ever recorded (dressed weight) with only a large Minnesota buck weighing in more, dressed (again, if my memory serves me).
Others have offered up a sighting of roughly 2 inches high at 100 yards as a good sighting scheme. In my own experience I have come to favor a sighting of 3.5 inches high at 100 yards. This allows for the individual to hold dead-on (directly in the middle of the top and bottom) the animal out to roughly 350 yards.
Magnum calibers such as the 7mm Remington and 300 Winchester will extend this slightly. At 400 yards I hold directly on the backbone of the animal. The drop at this range allows the...