I have used the Fusions out of my .270wsm with great results on deer. They shoot really good out of my rifle as well. My father shot a 4x5 raghorn bull with his .270wsm, 150gr fusions head on at 80 yards. Bullet entered right at the base of the bulls throat and we found the bullet resting against the hide on the right ham. Almost complete penetration lengthwise on a elk. I think it would do the trick if needed, but with that being said we both have switched to 140gr Accubonds as our all purpose round for hunting.