For a varmit rifle, I'd take the 22-250. The 25-06 works great but I see it more as a hunting cartridge. You could make whatever you want into a varmit rifle, I used a 338 win mag years ago. It was a hoot but a day with it sored ya up some. As you know I use a 243 now and I like it.
.22-250 or the .25-06. opinions on which is better? Would be for an all around varmit rifle.
Of the 2 you mentioned the .22/250 would be best - the key words are "all around". The .25/06 is a great cross over cartridge when deer are on the menu. Ditto on what ChesterGolf said about the .243, one my all time favorites.
Winter is tough on whitetails, that is an accepted fact.
You can help the quality of your herd by providing winter plots - that are not necessarily designed as kill plots.
Having what I call green plots - that the deer can browse in when most of the other food is gone, can greatly benefit the deer herd when they need it most.
Come December - at least in our area of the south - most of the mast is gone, all of the crops were long harvested and this green browse can really make the difference for...