The 45-70 is a better choice than the 444...no experence with the 450. Hotload the 45-70 with 405 grain jacketed to 2000 fps...you get about 3000 ft/lbs. Good to 150 yards. Never took a moose with my 45-70...just kept it behind the cabin door for quick bear medicine. I use a 338 Win mag or 300 Wby mag...alot of our shots are beyond 300 yards...work wonderful...drops moose like a bag of rocks.
I have never hunted moose with a lever action before, just whitetail deer. However I do own and hunt deer with the 444 Marlin. The only draw back would be the distance a hunter might have in taking their shot. It would be a 100 yard gun on moose, perhaps a 150 yard gun in the 45/70 caliber.
I have been on three hunting trip to Canada in moderate/heavy timber with Marlin 1895 45/70 with 350 grain Hornady bullets and found that at range's under 100 yards to be very deadly. I do how every think keeping the distance under 150 yds. 45/70 has a much better choice of bullets. I have had no experience with the 450 Marlin, don't see the needed already having a 45/70 that is, but would like to try out one of the guide guns Marlin offers.
I hunt mostly deer with the marlin 444, and it will shoot and cleanly kill to about 200yds. I have never shot a rifle that is more acurate than the 444 with nosler 240gr hollow points. prints clover leafs at 100yds. from center of each bullet hole the pattern was .320 " not bad for a bullet that measures in at .430". and thats no bull.
From the books that I have read, there is a lot of importance in knowing every nook and cranny of your hunting territory as well as the animal that you are hunting. So scouting as much as possible, just walking the land, will give you a good idea of what's around the corner or what's on the other side of a hill. Which can be very beneficial.
Making your own maps of human and deer trails, and different types of foliage such as group of pines,...