Hornady, for example, makes a variety of .22 caliber bullets weighing from 40 grains to 80 grains. The problem is, not all of these bullets may stabilize in the same rifle. They won't all stabilize in my .22-250. My Barnes manual states that a 1:12" twist or faster is required to stabilize their 45 and 53 grain bullets, but that twist will not stabilize their 62 and 70 grain bullets.
Many bullet manufacturers make hollow point bullets in a variety of weights for most of their calibers. Barnes even makes a 647 gr TSX (HP) bullet for the .50 BMG.
The 2013 Wyoming Big Game Hunting Regulations state: “When hunting antelope, deer, mountain lion, or grey wolf where designated as a trophy game animal, a hunter shall use any center-fire firearm of at least .22 caliber and having a bullet weight of at least sixty (60) grains and firing a cartridge of at least two (2) inches in overall length.”
The SAAMI specifications for the overall length of the .223 Rem is 2.165-2.26 inches. The .223 Rem is legal for deer in Wyoming.